All trials matter
All trials matter
Research Article
metrics
Revised
Influence of auditory-based cognitive training on auditory resolution, executive function, and working memory skills in individuals with mild cognitive impairment – a pilot randomized controlled study
[version 2; peer review: 1 approved, 3 approved with reservations]
Peer Reviewers
Karen Banai;
Sandeep Maruthy;
Sangamanatha Ankmnal Veeranna;
Dr Pinki Singh
- Funder
- Not Applicable
Study Protocol
metrics
Revised
Uptake of core outcome sets by clinical trialists in China: a protocol
[version 3; peer review: 2 approved]
Peer Reviewers
Zehuai Wen;
Kim Thomas and Emma Campbell
- Funders
- University of Liverpool
- Young Elite Scientists Sponsorship Program by CACM
- Qihuang Scholar of National Administration of Traditional Chinese Medicine
- MRC Trials Methodology Research Partnership
- National Natural Science Foundation of China
- National Institute for Health Research (NIHR) Senior Investigator Award
Research Article
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Clinical trial
Revised
Preventive efficacy of 38% silver diamine fluoride and CPP-ACP fluoride varnish on molars affected by molar incisor hypomineralization in children: A randomized controlled trial
[version 3; peer review: 2 approved]
Peer Reviewers
Peter Milgrom;
Juliana Souza
- Funder
- Damascus University
Study Protocol
metrics
Clinical trial
Single-centre, randomised clinical trial of the immunomodulatory mechanisms of daily supplementation of palm tocotrienol-rich fraction in healthy human volunteers following influenza vaccination
[version 1; peer review: 1 approved, 2 approved with reservations]
Peer Reviewers
Sonia Chew Wen Phang;
Philip C Calder;
Pablo Cañete and Emely Hernandez Mateo
- Funders
- Monash University Malaysia
- Excelvite Pte Ltd
- Malaysian Palm Oil Board
Research Article
metrics
Clinical trial
Revised
Effect of lactoferrin in oral nutrition supplement (ONS) towards IL-6 and IL-10 in failure to thrive children with infection
[version 3; peer review: 2 approved]
Peer Reviewers
Vinutha U. Muktamath;
Rachael Anyim and Mallory Peters
- Funder
- Universitas Airlangga
Study Protocol
metrics
Clinical trial
Revised
Effect of atorvastatin on subclinical atherosclerosis in virally-suppressed HIV-infected patients with CMV seropositivity: a randomized double-blind placebo-controlled trial
[version 2; peer review: 2 approved]
Peer Reviewers
Vicente Estrada;
Rudi Wisaksana
- Funder
- Kementerian Riset Teknologi Dan Pendidikan Tinggi Republik Indonesia
Research Article
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Clinical trial
Comparative evaluation of platelet rich fibrin matrix (PRFM) membrane and platelet rich fibrin (PRF) membrane using the vestibular incision subperiosteal tunnel access (VISTA) approach technique for the treatment of multiple gingival recession in humans: A double-blind, parallel-group, randomized controlled clinical trial
[version 1; peer review: 2 approved with reservations, 1 not approved]
Peer Reviewers
Gustavo Vicentis de Oliveira Fernandes;
Shiva Shankar Gummaluri;
Abhaya Chandra Das
Study Protocol
metrics
Clinical trial
Efficacy and safety of mizoribine in comparison with cyclophosphamide for treatment of lupus nephritis: Protocol for a multi-center, open-label, randomized controlled trial
[version 1; peer review: 1 approved, 1 approved with reservations]
Peer Reviewers
Liu Shuxin;
Desmond Yat Hin Yap
Study Protocol
metrics
Clinical trial
Revised
Protocol for the electroencephalography guidance of anesthesia to alleviate geriatric syndromes (ENGAGES-Canada) study: A pragmatic, randomized clinical trial
[version 2; peer review: 2 approved]
Peer Reviewers
Oluwaseun Johnson-Akeju;
Lian Kah Ti
- Funder
- Canadian Institutes of Health Research
Research Article
metrics
PEER REVIEW DISCONTINUED
Revised
How to promote ‘discipline without tough love’ during pregnancy: a randomized controlled trial
[version 3; peer review: 1 approved]
Peer Reviewers
Hiroko Iwata
- Funder
- Ministry of Health, Labour and Welfare
Study Protocol
metrics
Increase in colonic PRopionate as a method of prEVENTing weight gain in adults aged 20–40 years (iPREVENT): protocol of a multi-centre, double-blind, randomised, parallel-group trial to investigate the efficacy of inulin-propionate ester versus inulin (control) in the prevention of weight gain over 12 months
[version 1; peer review: 1 approved]
Peer Reviewers
Hoi Leong Xavier Wong
- Funder
- National Institute for Health Research (NIHR) Efficacy and Mechanism Evaluation Programme
Study Protocol
metrics
Clinical trial
Protocol for the Ketamine for Postoperative Avoidance of Depressive Symptoms (K-PASS) feasibility study: A randomized clinical trial
[version 1; peer review: 2 approved]
Peer Reviewers
Boris D Heifets;
Octavian Vasiliu
- Funders
- Foundation for Anesthesia Education and Research
- National Institute of Mental Health
Research Article
metrics
Clinical trial
Revised
The effect of triple antibiotic paste as an intracanal medication with an anti-inflammatory drug on post-operative pain of asymptomatic uniradicular necrotic teeth: a double blind randomized clinical trial
[version 2; peer review: 2 approved with reservations, 1 not approved]
Peer Reviewers
Maram E. Khallaf;
Jyothi Mandava and Ravichandra Ravi;
Mahalaxmi Sekar and Kritika Selvakumar
Study Protocol
metrics
Clinical trial
Revised
Modular intervention to improve paternal involvement and support for better infant and young child feeding in a district of coastal South India: a randomized controlled trial protocol
[version 2; peer review: 2 approved]
Peer Reviewers
Sudhir Prabhu H;
Amutha Ramadas
- Funders
- Public Health Foundation of India
- Department of Science and Technology (DST), Government of India
Research Article
metrics
Clinical trial
The effect of morning versus evening administration of empagliflozin on its pharmacokinetics and pharmacodynamics characteristics in healthy adults: a two-way crossover, non-randomised trial
[version 1; peer review: 2 approved, 1 approved with reservations]
Peer Reviewers
Hesham Basma;
Ashraf Abdel-Naim;
Samar Darwish
Study Protocol
metrics
Clinical trial
IMPORTANCE trial: a provisional study-design of a single-center, phase II, double-blinded, placebo-controlled, randomized, 4-week study to compare the efficacy and safety of intranasal esketamine in chronic opioid refractory pain
[version 1; peer review: 2 approved]
Peer Reviewers
Vinita Singh;
Danny Kupka
Study Protocol
metrics
PEER REVIEW DISCONTINUED
Clinical trial
Revised
The efficacy of acupuncture as a complementary treatment for pain and anxiety after breast cancer surgery: Study protocol for a pragmatic randomized control trial
[version 2; peer review: peer review discontinued]
Peer Reviewers
Invited
- Funder
- Societat Científica d’Acupuntura, Acadèmia de les Ciències Mèdiques de Catalunya i Balears
Research Article
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Clinical trial
Green tea influence on iron overload in thalassemia intermedia patients: a randomized controlled trial
[version 1; peer review: 2 approved]
Peer Reviewers
Alaa Alwan;
Hassan Abolghasemi
Research Article
metrics
Clinical trial
Negative/null result
Revised
Analgesic efficacy of intravenous nefopam after spine surgery: a randomized, double-blind, placebo-controlled trial
[version 2; peer review: 2 approved, 1 approved with reservations]
Peer Reviewers
Rattaphol Seangrung;
Francis Remérand;
Soe Wunna Htay
- Funder
- Prasat Neurological Institute
Study Protocol
metrics
Clinical trial
ACCEPT - combining acalabrutinib with rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone (R-CHOP) for Diffuse Large B-cell Lymphoma (DLBCL): study protocol for a Phase Ib/II open-label non-randomised clinical trial
[version 1; peer review: 2 approved]
Peer Reviewers
Allan Hackshaw;
Wendy Osborne
- Funders
- Cancer Research UK
- Acerta Pharma B.V.