About Endometriosis

Endometriosis is a chronic gynaecological condition affecting approximately 10% (190 million) of women and girls globally. It is defined by the presence of tissue similar to the lining of the uterus, or ‘endometrium’, growing outside of the uterus involving peritoneum (lining of the pelvis and abdomen), ovaries and other organs such as bowel, bladder, liver and diaphragms. The classical symptoms include pelvic pain, painful periods, and infertility.  Endometriosis causes a chronic inflammatory reaction that may result in life-impacting pain, formation of scar tissue, adhesions, and ovarian cysts.

Endometriosis is a complex disease with several hypotheses to explain its origin. Currently, there is no known cure for endometriosis, with most treatments only aiming to ease symptoms. Recurrence of endometriosis is common after both medical and surgical treatment. Further, access to this treatment is limited in low- and middle-income countries. Endometriosis still requires global research and public awareness to streamline prevention, early diagnosis, and improved management of the condition.

This collection aims to increase awareness and provide a platform for research in endometriosis, to create a space of innovation, shared knowledge, and open discussion in the field. We invite original clinical research and reviews focused on the diagnosis and treatment of endometriosis, as well as its social, psychological and health consequences.

Topics to include (but are not limited to):

• Pathogenesis of endometriosis
• Pathogenesis of endometriosis associated pain
• Cellular and immunological changes in endometriosis
• Diagnosis of endometriosis
• Surgical treatment of endometriosis
• Medical treatment of endometriosis
• Endometriosis-associated infertility
• Complementary therapies to manage endometriosis symptoms
• Novel therapies to treat endometriosis
• Association of endometriosis with other chronic conditions and cancer
• Adenomyosis
• Quality of life, emotional and psychological impact of endometriosis
• Societal and health care burden associated with endometriosis

Keywords:

• endometriosis; diagnosis; treatment; hormonal or medical therapy; laparoscopy; robotic surgery; health care planning; novel treatment; complementary therapies

Any questions about this collection? Please get in contact directly with research@f1000.com.