This collection is now closed to submissions.
Ancient DNA is the study of degraded DNA molecules extracted from substrates not specifically preserved for future genetic analyses. These can include ancient bones, teeth, soils, sediments, and museum specimens. Recent advancements in large-scale next-generation sequencing, combined with highly optimised wet-lab methods – including DNA extraction, library preparation, and target-capture methods – have enabled the regular retrieval and analysis of genome-wide data from ancient samples and specimens. This has revolutionised our understanding of many major prehistoric and historic events, including human evolution and the history and patterns of past migration and admixture, plant and animal domestication, changes in biodiversity and ecology, and the evolutionary histories of extinct organisms.
This content collection is dedicated to ancient DNA research published via the F1000Research platform. We welcome submissions (e.g., research articles, brief reports, method articles, and reviews) on ancient DNA-related research including, but not limited to, human/animal migrations, human adaptations, kinship analysis, microbes, evolution of diseases, changes in the diversity of wild populations through time, and methodological tweaks and developments, particularly research that is time-sensitive and requires rapid publication. Furthermore, as ancient DNA is riddled with difficulties, we also welcome null results that may be of use to the wider community, e.g. methodological tweaks that do not significantly improve output data quality, and sites where little to no DNA can be retrieved.
Keywords: Ancient DNA; sedaDNA; domestication; migration; admixture; extinction; microbiomes; adaptation; evolution
This collection is part of the
Cell & Molecular Biology and
Genomics and Genetics Gateways.
Any questions about this collection? Please get in contact directly with Sarah Rehman (sarah.rehman@f1000.com)