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Natural sciences comprises the branches of science which aim to describe and understand the fundamental processes and phenomena that define our natural world, including both life sciences and physical sciences.

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https://doi.org/10.12688/f1000research.169966.1
Data Note metrics AWAITING PEER REVIEW
A guide to selecting high-performing antibodies for Optineurin (UniProt ID: Q96CV9) for use in western blot, immunoprecipitation, and immunofluorescence
[version 1; peer review: awaiting peer review]
Vera Ruíz Moleón, Riham Ayoubi, Charles Alende, Maryam Fothouhi, Joel Ryan, Sara González Bolívar, Donovan Worrall, Thomas M Durcan, Claire M Brown, Vincent Francis, Peter S McPherson, Carl Laflamme
Peer Reviewers Invited
  • Funders
  • ALS Society of Canada
  • ALS Association
  • Motor Neurone Disease Association
  • Québec Consortium for Drug Discovery
PUBLISHED 17 Oct 2025
https://doi.org/10.12688/f1000research.171774.1
Study Protocol metrics AWAITING PEER REVIEW
Tracking the Evolving Role of Artificial Intelligence in Implementation Science: Protocol for a Living Scoping Review of Applications, Evaluation Approaches and Outcomes
[version 1; peer review: awaiting peer review]
Guillaume Fontaine, Olivia Di Lalla, Susan Michie, Byron J. Powell, Vivian Welch, James Thomas, Jeffery Chan, Samira Abbasgholizadeh-Rahimi, France Légaré, Janna Hastings, Sylvie D. Lambert, Justin Presseau, Sharon E. Straus, Ian D. Graham, Ruopeng An, Daniel N. Elakpa, Meagan Mooney, Alenda Dwiadila Matra Putra, Rachael Laritz, Natalie Taylor
Peer Reviewers Invited
PUBLISHED 17 Oct 2025
https://doi.org/10.12688/f1000research.167964.1
Case Study metrics AWAITING PEER REVIEW
Sneezing in response to naturalistic bright light exposure
[version 1; peer review: awaiting peer review]
Lucien Bickerstaff, Josef Trinkl, Stephan Munkwitz, Manuel Spitschan
Peer Reviewers Invited
  • Funder
  • Max-Planck-Gesellschaft
PUBLISHED 17 Oct 2025
https://doi.org/10.12688/f1000research.129581.2
Software Tool Article metrics
Revised
AmpSeqR: an R package for amplicon deep sequencing data analysis
[version 2; peer review: 1 approved, 2 approved with reservations]
Jiru Han, Jacob E. Munro, Melanie Bahlo
Peer Reviewers Eduardo Castro-Nallar; Cristian Koepfli and Gustavo Da Silva; Patrick Murigu Kamau Njage
  • Funders
  • Institute Infrastructure Support Scheme (IRIISS)
  • National Health and Medical Research Council
LATEST VERSION PUBLISHED 17 Oct 2025
https://doi.org/10.12688/f1000research.166881.1
Research Article metrics AWAITING PEER REVIEW
Integration of Break Dance and Computational Physics: An Interdisciplinary Approach to Contextualized Teaching
[version 1; peer review: awaiting peer review]
Juan José Velandia Huérfano, Diego Fernando Becerra Rodriguez, Óscar Rafael Boude Figueredo, Ana Dolores Vargas Sánchez, Mario Humberto Ramírez Díaz
Peer Reviewers Invited
  • Funder
  • Universidad de La Sabana
PUBLISHED 17 Oct 2025
https://doi.org/10.12688/f1000research.140134.2
Genome Note metrics
Revised
The complete chloroplast genome of Phyllanthus acidus (L.) Skeels (Phyllanthaceae)
[version 2; peer review: 1 approved with reservations]
Hoang Danh Nguyen, Thi Diem Quynh Nguyen, Minh Thiet Vu, Hoang Dang Khoa Do
Peer Reviewers Jessica D. Rey
  • Funder
  • Nguyen Tat Thanh University
LATEST VERSION PUBLISHED 16 Oct 2025
https://doi.org/10.12688/f1000research.160416.3
Research Article metrics
Revised
Ginkgo Biloba as a niche theme cognitive enhancer agent, 1420 dokumen of Scopus database. A bibliometric study from 1988 to 2024
[version 3; peer review: 1 approved, 1 approved with reservations]
ARMAN YURISALDI SALEH, Dwi Arwandi Yogi Saputra, Riezky Valentina, Tirta Darmawan Susanto
Peer Reviewers Tasawar Iqbal; Arne Reimers
LATEST VERSION PUBLISHED 15 Oct 2025
https://doi.org/10.12688/f1000research.168964.1
Software Tool Article metrics AWAITING PEER REVIEW
MOODMIND: Artificial Intelligence for Major Depressive Disorder Screening in Tuberculosis Patients
[version 1; peer review: awaiting peer review]
Erlina Wijayanti, Ammar Abror, Ummi Azizah Rachmawati, Citra Fitri Agustina, Helwiah Umniyati, Diana Batara Munti, Exir Najib Rahmat, Athoillah Ahkam Diansyah
Peer Reviewers Invited
  • Funder
  • YARSI University
PUBLISHED 13 Oct 2025
https://doi.org/10.12688/f1000research.154021.2
Research Article metrics
Revised
Alpha-guaiene isolated from patchouli oil exhibits antifungal activity against four pathogenic fungi
[version 2; peer review: 2 approved with reservations]
Sarifah Nurjanah, Zhaqqu Alhafidz, Maghfira Maulani, Tita Rialita, Elazmanawati Lembong
Peer Reviewers Irmanida Batubara; Harlinda Kuspradini
  • Funder
  • Universitas Padjadjaran-RKDU
LATEST VERSION PUBLISHED 13 Oct 2025
https://doi.org/10.12688/f1000research.168556.1
Research Article metrics AWAITING PEER REVIEW
Single-cell RNA sequencing of cerebrospinal fluid reveals the expansion of innate lymphoid cells with upregulated transposable elements in multiple sclerosis
[version 1; peer review: awaiting peer review]
Pouria Mosaddeghi, Mitra Farahmandnejad, Mohammad M. Zarshenas
Peer Reviewers Invited
  • Funder
  • Shiraz University of Medical Sciences
PUBLISHED 10 Oct 2025
https://doi.org/10.12688/f1000research.168673.1
Systematic Review metrics AWAITING PEER REVIEW
Evaluating artificial intelligence for accurate detection of hand and wrist fractures: a systematic review and meta-analysis
[version 1; peer review: awaiting peer review]
Hamed Alosaimi, Abdullah Musaaed Alsalamah, Nawwaf N. Alharbi, Hashim Albar, Mohammed Khalid I. Alghamdi, Sultan Abdulaziz Alnuman, Anas M. Alrashed, Omar H Bin Salleeh, Khalid Abdullah Alharbi, Malik Raja Alanazi, Weaam Hamoud Alqabasani, Shahad Abdullah Nolelli, Mohammed Saeed Alharbi
Peer Reviewers Invited
PUBLISHED 10 Oct 2025
https://doi.org/10.12688/f1000research.166678.1
Research Article metrics AWAITING PEER REVIEW
Exploring the Potential of Peptides Derived from the Coelomic Fluid of Echinometra lucunter Targeting Inflammatory Cytokines in Placental Syndromes: In Silico Study
[version 1; peer review: awaiting peer review]
Defrin Defrin, Arif Birru, Kevin Cuandra, Ratna Puspita, I Widnyana, Nasya Aqilah, Arzita Fadhilla, Winka Suwardjo, Amanda Amalia, Kalaj Haq, Tirza Amaris, Feroz Aldino, Shabrina Ekitasari, Bernice Sirait, Nathania Kristaningtyas, Rizka Wilanda, Made Ananda
Peer Reviewers Invited
PUBLISHED 10 Oct 2025
https://doi.org/10.12688/f1000research.170127.1
Research Article metrics AWAITING PEER REVIEW
A Generic Requirement Engineering Framework for Social Commerce Platforms: Front-end and Back-end Features
[version 1; peer review: awaiting peer review]
Iman Al Jassasi, Youcef Baghdadi, Abdullah Al Hamdani
Peer Reviewers Invited
  • Funder
  • Sultan Qaboos University
PUBLISHED 09 Oct 2025
https://doi.org/10.12688/f1000research.170680.1
Review metrics AWAITING PEER REVIEW
Integrating spatial omics with routine haematoxylin and eosin in formalin-fixed paraffin-embedded: a step-by-step clinical workflow
[version 1; peer review: awaiting peer review]
Nasar Alwahaibi
Peer Reviewers Invited
  • Funder
  • None
PUBLISHED 09 Oct 2025
https://doi.org/10.12688/f1000research.125877.3
Research Article metrics
Revised
General anaesthetics reduce acute lymphoblastic leukaemia malignancies in vitro and in vivo via CXCR4 and osteopontin mediated mechanisms
[version 3; peer review: 1 approved, 2 approved with reservations]
Cui Jiang, Sara Gonzalez-Anton, Xiaomeng Li, Emma Mi, Lingzhi Wu, Hailin Zhao, Ge Zhang, Aiping Lu, Cristina Lo Celso, Daqing Ma
Peer Reviewers Koichi Yuki; Paul M Maciocia and Jongwon Yoon; Victor H. Villar Cortes
  • Funders
  • Cancer Research UK
  • UK and European Research Council
  • Royal College of Anaesthetists
LATEST VERSION PUBLISHED 09 Oct 2025
https://doi.org/10.12688/f1000research.149941.2
Research Article metrics
Revised
Planet activeness: a new concept to enhance the accuracy of Astromet weather forecast.
[version 2; peer review: 1 approved with reservations]
Dheebakaran Ga, Kokilavani S, Santosh Ganapati Patil, Sankar T, Rathika K, Arul Prasath S, Balamurali B, Sathyamoorthy N.K.
Peer Reviewers Shankarappa Sridhara
LATEST VERSION PUBLISHED 09 Oct 2025
https://doi.org/10.12688/f1000research.157192.3
Policy Brief metrics
Revised
Renewable energy: A way out for South Sudan’s electricity crisis
[version 3; peer review: 2 approved]
Aban Ayik, Nelson Ijumba
Peer Reviewers Barnaby Joseph Dye; Taco Niet
LATEST VERSION PUBLISHED 08 Oct 2025
https://doi.org/10.12688/f1000research.169383.1
Research Article metrics AWAITING PEER REVIEW
Effect of combined hurdle technology treatments on the quality characteristics of minimally processed pitahaya 
[version 1; peer review: awaiting peer review]
Nicodemo Jamanca-Gonzales, Robert Ocrospoma-Dueñas, Eulalia Vargas-Tapia, Yolanda Eguilas-Caushi, Thalia A. Rivera-Ashqui, Reynaldo J. Silva-Paz
Peer Reviewers Invited
  • Funder
  • Universidad Nacional de Barranca
PUBLISHED 08 Oct 2025
https://doi.org/10.12688/f1000research.169308.1
Research Article metrics
Bromelain Restores Glutamatergic Homeostasis via Regulation of NR2A, GLT-1, EAAC1, and xCT in Arsenic-Induced Cerebral Cortex and Hippocampal Neurotoxicity
[version 1; peer review: 1 approved with reservations]
Emeka Godson Anyanwu, Kpokuechukwu Chinua Ogonnadi, Augustine Uchenna Agu, Nto Johnson Nto, Ikechukwu Aniaku, Yadilichi Yvonne Nwabueze, Vivian Onyinye Ojiakor, Chinyere N Anyanwu
Peer Reviewers Yousef Mohammed Aljohani
PUBLISHED 07 Oct 2025
https://doi.org/10.12688/f1000research.145171.3
Research Article metrics
Revised
Tumor-driven stromal reprogramming in the pre-metastatic lymph node
[version 3; peer review: 1 approved, 1 approved with reservations]
Michelle Piquet, David A Ruddy, Viviana Cremasco, Jonathan Chang
Peer Reviewers Sanjiv Luther; Christopher McGinnis
LATEST VERSION PUBLISHED 07 Oct 2025
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