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Natural sciences comprises the branches of science which aim to describe and understand the fundamental processes and phenomena that define our natural world, including both life sciences and physical sciences.

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 in 
https://doi.org/10.12688/f1000research.23547.2
Research Article metrics
Revised
Human umbilical cord blood-mesenchymal stem cell-derived secretome in combination with atorvastatin enhances endothelial progenitor cells proliferation and migration
[version 2; peer review: 2 approved]
Yudi Her Oktaviono, Suryo Ardi Hutomo, Makhyan Jibril Al-Farabi, Angliana Chouw, Ferry Sandra
Peer Reviewers Anwar Santoso; Anwar Tandar
  • Funder
  • Prodia Education and Research Institute
LATEST VERSION PUBLISHED 10 May 2021
https://doi.org/10.12688/f1000research.27500.2
Opinion Article metrics
Revised
The need for standardisation in life science research - an approach to excellence and trust.
[version 2; peer review: 3 approved]
Susanne Hollmann, Andreas Kremer, Špela Baebler, Christophe Trefois, Kristina Gruden, Witold R. Rudnicki, Weida Tong, Aleksandra Gruca, Erik Bongcam-Rudloff, Chris T. Evelo, Alina Nechyporenko, Marcus Frohme, David Šafránek, Babette Regierer, Domenica D'Elia
Peer Reviewers David Nickerson; Laurent Falquet; Antonella Lanati
  • Funder
  • Horizon 2020
LATEST VERSION PUBLISHED 10 May 2021
https://doi.org/10.12688/f1000research.51433.1
Case Report metrics
Case Report: Guitarist’s cramp as the initial manifestation of dopa-responsive dystonia with a novel heterozygous GCH1 mutation
[version 1; peer review: 2 approved, 1 approved with reservations]
Takafumi Hasegawa, Tatsuhiko Hosaka, Ryuhei Harada, Ichiro Kawahata, Kyoko Hoshino, Naoto Sugeno, Akio Kikuchi, Masashi Aoki
Peer Reviewers Hiroshi Ichinose; Taku Hatano; Juei-Jueng Lin
  • Funders
  • The Kawano Masanori Memorial Foundation for Promotion of Pediatrics
  • Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan
PUBLISHED 07 May 2021
https://doi.org/10.12688/f1000research.52141.1
Software Tool Article metrics AWAITING PEER REVIEW
Restriction site-associated DNA from Python-implemented Digestion Simulations (RApyDS): a companion tool for RAD sequencing experimental design
[version 1; peer review: awaiting peer review]
Kristianne Arielle Gabriel, Maria Rejane Nepacina, Francis Tablizo, Carlo Lapid, Mark Lenczner Mendoza, Daniella Jean Pamulaklakin, Jobeth Domingo, Marc Jermaine Pontiveros, Hannah Mae Magno, Joshua Gregor Dizon, El King Morado, Jan Michael Yap
Peer Reviewers Invited
  • Funder
  • Philippine Council for Industry, Energy and Emerging Technology Research and Development of the Department of Science and Technology
PUBLISHED 07 May 2021
https://doi.org/10.12688/f1000research.51874.1
Research Article metrics
Horizontal transfer and evolution of wall teichoic acid gene cassettes in Bacillus subtilis
[version 1; peer review: 1 approved, 2 approved with reservations]
Granger Sutton, Gary B. Fogel, Bradley Abramson, Lauren Brinkac, Todd Michael, Enoch S. Liu, Sterling Thomas
Peer Reviewers Jeffrey B. Jones; José Escudero; Patrick Eichenberger
  • Funders
  • IARPA
  • Office of the Director of National Intelligence
PUBLISHED 07 May 2021
https://doi.org/10.12688/f1000research.51407.1
Case Report metrics
Case Report: A five-year follow up after pediatric renal transplantation using flow cytometry crossmatch and HLA immunophenotyping based on DNA for screening test
[version 1; peer review: 2 approved, 1 approved with reservations, 1 not approved]
Johanes Dwi Meiyanto, Besut Daryanto, Kurnia Penta Seputra
Peer Reviewers Ali Ersin Zumrutbas; Nur Rasyid; Nicolas Guillaume; Shigeo Horie
PUBLISHED 06 May 2021
https://doi.org/10.12688/f1000research.28187.1
Method Article metrics
Validity and reliability of method used to analyse hair cortisol concentration
[version 1; peer review: 2 approved with reservations]
Jordan Reid, Katy Parker, Lydia Clemens, Matt Bristow
Peer Reviewers Yolanda B. de Rijke; Gabriela Berg and Bibiana Fabre
PUBLISHED 06 May 2021
https://doi.org/10.12688/f1000research.27952.2
Research Article metrics
Revised
Cytotoxic T cells response with decreased CD4/CD8 ratio during mammary tumors inhibition in rats induced by non-contact electric fields
[version 2; peer review: 2 approved]
Firman Alamsyah, Rarastoeti Pratiwi, Nisrina Firdausi, Jessica Irene Mesak Pello, Subekti Evi Dwi Nugraheni, Ahmad Ghitha Fadhlurrahman, Luthfi Nurhidayat, Warsito Purwo Taruno
Peer Reviewers Bilgin Keserci; Elfahmi Elfahmi
  • Funders
  • Ctech Labs Edwar Technology
  • Indonesian Ministry of Research, Technology and Higher Education
LATEST VERSION PUBLISHED 04 May 2021
https://doi.org/10.12688/f1000research.27393.3
Brief Report metrics
Revised
Towards establishing extracellular vesicle-associated RNAs as biomarkers for HER2+ breast cancer
[version 3; peer review: 3 approved]
Colin L. Hisey, Petr Tomek, Yohanes N.S. Nursalim, Lawrence W. Chamley, Euphemia Leung
Peer Reviewers Nagarajan Kannan; Tracy K. Hale; Bruno M. Simoes
  • Funders
  • New Zealand Breast Cancer Foundation
  • Cancer Research Trust New Zealand
  • Faculty of Medical and Health Sciences, University of Auckland
LATEST VERSION PUBLISHED 04 May 2021
https://doi.org/10.12688/f1000research.50738.2
Research Article metrics
Revised
Risk factors for major external structural birth defects among children in Kiambu County, Kenya: a case-control study
[version 2; peer review: 2 approved, 1 approved with reservations]
George N. Agot, Marshal M. Mweu, Joseph K. Wang'ombe
Peer Reviewers Yoseph Worku; Marcia L. Feldkamp; Rogath Kishimba
LATEST VERSION PUBLISHED 30 Apr 2021
https://doi.org/10.12688/f1000research.47068.1
Research Article metrics
The existence and characteristics of rats and shrews in endemic leptospirosis areas and types of ectoparasites: a case study of West Jakarta, Indonesia
[version 1; peer review: 2 approved, 1 not approved]
Dewi Susanna, Rusyda Ihwani Tantia Nova, Laura Rozek
Peer Reviewers Malina Osman; Philip Samuel Paulraj; Rahayu Lubis
  • Funder
  • Publikasi Terindeks Internasional (PUTI) Kolaborasi Internasional (2Q2)
PUBLISHED 30 Apr 2021
https://doi.org/10.12688/f1000research.25485.1
Opinion Article metrics
Highlights from the 2016-2020 NEUBIAS training schools for Bioimage Analysts: a success story and key asset for analysts and life scientists
[version 1; peer review: 2 approved]
Gabriel G. Martins, Fabrice P. Cordelières, Julien Colombelli, Rocco D’Antuono, Ofra Golani, Romain Guiet, Robert Haase, Anna H. Klemm, Marion Louveaux, Perrine Paul-Gilloteaux, Jean-Yves Tinevez, Kota Miura
Peer Reviewers Thorsten Wohland; Kevin Eliceiri
  • Funders
  • Swedish Foundation for Strategic Research
  • Fundação para a Ciência e a Tecnologia
  • COST
  • Luxembourg National Research Fund
  • Cancer Research UK
  • Deutsche Forschungsgemeinschaft
  • Swedish National Microscopy infrastructure
  • UK Medical Research Council
  • France BioImaging national infrastructure
  • Wellcome Trust
PUBLISHED 30 Apr 2021
https://doi.org/10.12688/f1000research.51732.1
Software Tool Article metrics
ImageM: a user-friendly interface for the processing of multi-dimensional images with Matlab
[version 1; peer review: 2 approved with reservations]
David Legland, Marie-Françoise Devaux
Peer Reviewers John Anthony Jose and Janos Lance Tiberio; Curtis Rueden
PUBLISHED 30 Apr 2021
https://doi.org/10.12688/f1000research.52569.1
Opinion Article metrics
Bioimage analysis workflows: community resources to navigate through a complex ecosystem
[version 1; peer review: 2 approved]
Perrine Paul-Gilloteaux, Sébastien Tosi, Jean-Karim Hériché, Alban Gaignard, Hervé Ménager, Raphaël Marée, Volker Baecker, Anna Klemm, Matúš Kalaš, Chong Zhang, Kota Miura, Julien Colombelli
Peer Reviewers Katy Wolstencroft; Assaf Zaritsky
  • Funder
  • Agence Nationale de la Recherche
PUBLISHED 26 Apr 2021
https://doi.org/10.12688/f1000research.28402.1
Research Article metrics
Jellyfish (Aurelia aurita) collagen scaffolds potential in alveolar bone regeneration
[version 1; peer review: 2 approved with reservations]
Ranny Rachmawati, Mohammad Hidayat, Nur Permatasari, Sri Widyarti
Peer Reviewers Ika Dewi Ana; Mike Barbeck
  • Funder
  • Universitas Brawijaya
PUBLISHED 23 Apr 2021
https://doi.org/10.12688/f1000research.21072.2
Research Article metrics
Revised
A bioactive compound isolated from Duku (Lansium domesticum Corr) fruit peels exhibits cytotoxicity against T47D cell line
[version 2; peer review: 2 approved]
Khusnul Fadhilah, Subagus Wahyuono, Puji Astuti
Peer Reviewers Ratana Banjerdpongchai; Deden Derajat Matra
  • Funder
  • Kementerian Riset, Teknologi dan Pendidikan Tinggi
LATEST VERSION PUBLISHED 23 Apr 2021
https://doi.org/10.12688/f1000research.52954.1
Retraction metrics NOT PEER REVIEWED
RETRACTED: A low-cost in-house HIV integrase strand transfer inhibitor drug resistance test for resource-limited settings
[version 1; peer review: not peer reviewed]
Vera M. Onwong'a, Rachael W. Gachogo, Moses M. Masika, Graeme B. Jacobs, Frank G. Onyambu
  • Funder
  • Interhealth Networks Africa scholarship INA-001
PUBLISHED 20 Apr 2021
https://doi.org/10.12688/f1000research.52531.1
Opinion Article metrics
Developing open-source software for bioimage analysis: opportunities and challenges
[version 1; peer review: 2 approved]
Florian Levet, Anne E. Carpenter, Kevin W. Eliceiri, Anna Kreshuk, Peter Bankhead, Robert Haase
Peer Reviewers Loïc A. Royer; Nico Stuurman
  • Funders
  • Deutsche Forschungsgemeinschaft
  • Institut National de la Santé et de la Recherche Médicale
  • National Institutes of Health
  • Chan Zuckerberg Initiative
PUBLISHED 19 Apr 2021
https://doi.org/10.12688/f1000research.28608.2
Method Article metrics
Revised
ASaiM-MT: a validated and optimized ASaiM workflow for metatranscriptomics analysis within Galaxy framework
[version 2; peer review: 2 approved]
Subina Mehta, Marie Crane, Emma Leith, Bérénice Batut, Saskia Hiltemann, Magnus Ø Arntzen, Benoit J. Kunath, Phillip B. Pope, Francesco Delogu, Ray Sajulga, Praveen Kumar, James E. Johnson, Timothy J. Griffin, Pratik D. Jagtap
Peer Reviewers Caitlin Simopoulos; Won Kyong Cho
  • Funders
  • National Cancer Institute
  • University of Minnesota
  • National Science Foundation
LATEST VERSION PUBLISHED 19 Apr 2021
https://doi.org/10.12688/f1000research.26486.3
Research Article metrics
Revised
Neurons with dendrites can perform linearly separable computations with low resolution synaptic weights
[version 3; peer review: 3 approved]
Romain D. Cazé, Marcel Stimberg
Peer Reviewers Sacha van Albada; Fleur Zeldenrust; Alexandra Tzilivaki and Panayiota Poirazi
  • Funders
  • IHU FOReSIGHT
  • LabEx LIFESENSES
LATEST VERSION PUBLISHED 18 Apr 2021
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