Natural Sciences

Natural sciences comprises the branches of science which aim to describe and understand the fundamental processes and phenomena that define our natural world, including both life sciences and physical sciences.

All Research Articles

2,521-2,540 of 5,766 ARTICLES
https://doi.org/10.12688/f1000research.21589.1
Correspondence metrics
Detection of compound heterozygous variants in LPIN1 does not necessarily imply pathogenicity in a patient with rhabdomyolysis
[version 1; peer review: 4 approved]
Peer Reviewers Panupong Hansrivijit; Karolina M Stepien; Pushpa Raj Joshi; Chiara Pizzamiglio
PUBLISHED 13 Jan 2020
https://doi.org/10.12688/f1000research.19803.2
Antibody Validation Article metrics
Revised
Validation of a commercial antibody to detect endogenous human nicastrin by immunoblot
[version 2; peer review: 2 approved, 1 approved with reservations]
Peer Reviewers Satoru Funamoto; Lucia Chavez-Gutierrez; Jongkyun Kang
  • Funders
  • National Center for Advancing Translational Sciences
  • National Institute of Arthritis and Musculoskeletal and Skin Diseases
LATEST VERSION PUBLISHED 10 Jan 2020
https://doi.org/10.12688/f1000research.21773.1
Software Tool Article metrics
Pharmosome: an integrative and collective database for exploration and analysis of single nucleotide polymorphisms associated with disease
[version 1; peer review: 2 approved with reservations]
Peer Reviewers Fuyi Li; Mulin Jun Li
PUBLISHED 10 Jan 2020
https://doi.org/10.12688/f1000research.21431.1
Case Report metrics
Case Report: Pseudoxanthoma elasticum
[version 1; peer review: 1 approved, 3 approved with reservations]
Peer Reviewers Olivier M. Vanakker; Márta Medvecz; Annamaria Offidani; Wilko Spiering
PUBLISHED 09 Jan 2020
https://doi.org/10.12688/f1000research.18445.2
Research Article metrics
Revised
DNA interference by a mesophilic Argonaute protein, CbcAgo
[version 2; peer review: 2 approved]
Peer Reviewers Eduardo Santero and Inés Canosa; Nathan A. Tanner
  • Funders
  • Fundación Ramón Areces
  • Spanish Ministry of Economy and Competitiveness
LATEST VERSION PUBLISHED 09 Jan 2020
https://doi.org/10.12688/f1000research.18861.2
Method Article metrics
Revised
Construction and optimization of a ‘NG Morbidostat’ - An automated continuous-culture device for studying the pathways towards antibiotic resistance in Neisseria gonorrhoeae
[version 2; peer review: 2 approved]
Peer Reviewers William M. Shafer; Olusegun O. Soge
  • Funder
  • Institute of Tropical Medicine
LATEST VERSION PUBLISHED 08 Jan 2020
https://doi.org/10.12688/f1000research.20563.1
Review metrics
Flavohaemoglobin: the pre-eminent nitric oxide–detoxifying machine of microorganisms
[version 1; peer review: 6 approved]
Peer Reviewers Andrés Vázquez-Torres; Mark P. Brynildsen; John S. Olson; Marie-Alda Gilles-Gonzalez; Elizabeth M. Boon; Vinai C. Thomas
  • Funder
  • Biotechnology and Biological Sciences Research Council
PUBLISHED 08 Jan 2020
https://doi.org/10.12688/f1000research.19766.4
Research Article metrics
Revised
Next-generation sequencing of microbial cell-free DNA for rapid noninvasive diagnosis of infectious diseases in immunocompromised hosts
[version 4; peer review: 3 approved]
Peer Reviewers William Muller; Dimitrios Farmakiotis; Steve Miller
LATEST VERSION PUBLISHED 06 Jan 2020
https://doi.org/10.12688/f1000research.21804.1
Research Article metrics
Clinical trial
A phase 2 open-label study of carboplatin in combination with gemcitabine as a dose-dense schedule in patients with locally advanced or metastatic breast cancer that are resistant to anthracyclines and taxanes
[version 1; peer review: 2 approved with reservations]
Peer Reviewers Lubna N. Chaudhary; Caroline Hamm
  • Funder
  • Eli Lilly and Company
PUBLISHED 06 Jan 2020
https://doi.org/10.12688/f1000research.19826.1
Review metrics
Duplex kidney formation: developmental mechanisms and genetic predisposition
[version 1; peer review: 2 approved]
Peer Reviewers Norman Rosenblum; Satu Kuure
  • Funder
  • La Ligue Contre le Cancer
PUBLISHED 06 Jan 2020
https://doi.org/10.12688/f1000research.19149.2
Case Report metrics
Revised
Case Report: Cetuximab and nivolumab use in advanced cutaneous squamous cell carcinoma resistant to chemotherapy
[version 2; peer review: 2 approved]
Peer Reviewers Gregory A Daniels; Gloria Orlando
  • Funder
  • Associazione Romana Ricerca Dermatologica
LATEST VERSION PUBLISHED 31 Dec 2019
https://doi.org/10.12688/f1000research.14848.2
Case Report metrics
Revised
Case Report: Large ileal intramural hematoma presenting as an intestinal obstruction in a patient on Warfarin with incidental breast cancer
[version 2; peer review: 2 approved]
Peer Reviewers Kevin W. Olden; Everton Cazzo
LATEST VERSION PUBLISHED 30 Dec 2019
https://doi.org/10.12688/f1000research.20387.1
Review metrics
Recent advances in liver transplantation with HCV seropositive donors
[version 1; peer review: 2 approved]
Peer Reviewers Marina C Berenguer; Paul Martin
  • Funder
  • National Institutes of Health
PUBLISHED 30 Dec 2019
https://doi.org/10.12688/f1000research.20942.1
Review metrics
Desmosomes:  Essential contributors to an integrated intercellular junction network
[version 1; peer review: 2 approved]
Peer Reviewers Alexa Mattheyses; Thomas Magin
  • Funders
  • National Institute of Arthritis and Musculoskeletal and Skin Diseases
  • American Heart Association
  • Joseph L. Mayberry Endowment
  • National Cancer Institute
PUBLISHED 30 Dec 2019
https://doi.org/10.12688/f1000research.21797.1
Research Article metrics
Using synthetic datasets to bridge the gap between the promise and reality of basing health-related decisions on common single nucleotide polymorphisms
[version 1; peer review: 1 approved, 1 approved with reservations]
Peer Reviewers Yesim Aydin Son; Oliver Pain
  • Funder
  • Department of Pediatrics, University of Washington
PUBLISHED 30 Dec 2019
https://doi.org/10.12688/f1000research.20094.1
Review metrics
What do archaeal and eukaryotic histidine kinases sense?
[version 1; peer review: 3 approved]
Peer Reviewers Wei Qian; Jeffrey J. Tabor; Sean Crosson
  • Funder
  • National Institutes of Health
PUBLISHED 27 Dec 2019
https://doi.org/10.12688/f1000research.21180.1
Review metrics
LEAFY COTYLEDONs: old genes with new roles beyond seed development
[version 1; peer review: 2 approved]
Peer Reviewers Loïc Lepiniec; Miriam Calonje Macaya
  • Funders
  • Chinese Academy of Sciences
  • National Natural Science Foundation of China
PUBLISHED 27 Dec 2019
https://doi.org/10.12688/f1000research.21763.1
Software Tool Article metrics
vhcub: Virus-host codon usage co-adaptation analysis
[version 1; peer review: 2 approved]
Peer Reviewers Raj Kumar Singh; Oscar Leonardo Ramírez Suárez and Adriana Patricia Corredor-Figueroa
PUBLISHED 23 Dec 2019
https://doi.org/10.12688/f1000research.21568.1
Editorial metrics NOT PEER REVIEWED
BOSC 2019, the 20th annual Bioinformatics Open Source Conference
[version 1; peer review: not peer reviewed]
PUBLISHED 20 Dec 2019
https://doi.org/10.12688/f1000research.21065.1
Review metrics
Sec translocon has an insertase-like function in addition to polypeptide conduction through the channel
[version 1; peer review: 4 approved]
Peer Reviewers Ross Dalbey; Gunnar von Heijne; Richard Zimmermann; Arnold J M Driessen
  • Funder
  • MEXT and JSPS
PUBLISHED 20 Dec 2019
2,521-2,540 of 5,766 ARTICLES
Articles
We publish a wide range of article types in science, engineering, medicine, social sciences and humanities, with no editorial biases.
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