Natural Sciences

Natural sciences comprises the branches of science which aim to describe and understand the fundamental processes and phenomena that define our natural world, including both life sciences and physical sciences.

All Research Articles

2,081-2,100 of 5,762 ARTICLES
https://doi.org/10.12688/f1000research.26170.2
Research Article metrics
Revised
Development of species-specific SCAR markers for identification and authentication of three rare Peninsular Malaysian endemic Coelogyne (Orchidaceae) orchids
[version 2; peer review: 2 approved]
Peer Reviewers Mohd Norfaizal Ghazali; Jean Wan Hong Yong
  • Funder
  • Universiti Putra Malaysia
LATEST VERSION PUBLISHED 05 Jan 2021
https://doi.org/10.12688/f1000research.26880.2
Software Tool Article metrics
Revised
Recursive Cluster Elimination based Rank Function (SVM-RCE-R) implemented in KNIME
[version 2; peer review: 3 approved]
Peer Reviewers Marco Chierici; Osman Ugur Sezerman; Abhishek Kumar
  • Funder
  • National Cancer Institute
LATEST VERSION PUBLISHED 05 Jan 2021
https://doi.org/10.12688/f1000research.19080.2
Study Protocol metrics
Revised
A recall-by-genotype study on polymorphisms in the TMPRSS6 gene and oral iron absorption: a study protocol
[version 2; peer review: 1 approved, 1 approved with reservations]
Peer Reviewers Dale R. Nyholt and Hamzeh MESRIAN TANHA; Alida Melse-Boonstra
  • Funders
  • Department for International Development
  • Medical Research Council UK
LATEST VERSION PUBLISHED 04 Jan 2021
https://doi.org/10.12688/f1000research.23390.2
Software Tool Article metrics
Revised
Seqpare: a novel metric of similarity between genomic interval sets
[version 2; peer review: 2 approved]
Peer Reviewers Zhaohui Steve Qin; Burcak Otlu
LATEST VERSION PUBLISHED 04 Jan 2021
https://doi.org/10.12688/f1000research.26659.1
Research Article metrics
Cloning of human ABCB11 gene in E. coli required the removal of an intragenic Pribnow-Schaller Box before it’s Insertion into genomic safe harbor AAVS1 site using CRISPR–Cas9
[version 1; peer review: 2 approved]
Peer Reviewers Mitradas Panicker; Nagendra Chaturvedi
  • Funders
  • Science and Engineering Research Board
  • Department of Biotechnology, Ministry of Science and Technology, India
PUBLISHED 23 Dec 2020
https://doi.org/10.12688/f1000research.27217.2
Opinion Article metrics
Revised
Cancer T-cell therapy: building the foundation for a cure
[version 2; peer review: 3 approved]
Peer Reviewers John R. James and Muna Fuyal; Barbra J. Sasu; C. Glenn Begley
  • Funder
  • A2 Biotherapeutics, Inc.
LATEST VERSION PUBLISHED 22 Dec 2020
https://doi.org/10.12688/f1000research.26632.1
Research Article metrics
Glibenclamide, ATP and metformin increases the expression of human bile salt export pump ABCB11
[version 1; peer review: 1 approved, 2 approved with reservations]
Peer Reviewers Premkumar Kumpati; Jayanta Roy-Chowdhury; Amit Dash
  • Funders
  • Science and Engineering Research Board
  • Department of Biotechnology, Ministry of Science and Technology, India
PUBLISHED 22 Dec 2020
https://doi.org/10.12688/f1000research.20038.2
Research Article metrics
Revised
Predicting the chances of live birth for couples undergoing IVF-ICSI: a novel instrument to advise patients and physicians before treatment
[version 2; peer review: 1 approved with reservations, 2 not approved]
Peer Reviewers Charalampos Siristatidis; Jichun Tan; Edwin Amalraj Raja
  • Funder
  • Portuguese Foundation for Science and Technology
LATEST VERSION PUBLISHED 22 Dec 2020
https://doi.org/10.12688/f1000research.21216.2
Clinical Practice Article metrics
Revised
Case report: Treating a co-existence of hidradenitis suppurativa and psoriasis with different therapeutic approaches
[version 2; peer review: 3 approved]
Peer Reviewers Thrasyvoulos Tzellos; Georgios Nikolakis; Kevin K. Wu
LATEST VERSION PUBLISHED 22 Dec 2020
https://doi.org/10.12688/f1000research.23829.2
Research Article metrics
Revised
Computational screening for potential drug candidates against the SARS-CoV-2 main protease
[version 2; peer review: 2 approved]
Peer Reviewers Murtaza Tambuwala; Alaa A A Aljabali
  • Funder
  • Conselho Nacional de Desenvolvimento Científico e Tecnológico
LATEST VERSION PUBLISHED 21 Dec 2020
https://doi.org/10.12688/f1000research.27171.1
Software Tool Article metrics
Bleach correction ImageJ plugin for compensating the photobleaching of time-lapse sequences
[version 1; peer review: 4 approved, 1 approved with reservations]
Peer Reviewers Fabrice P Cordelières; Arianne Bercowsky Rama; Thomas Pengo; Anna H. Klemm; Bram van den Broek
PUBLISHED 21 Dec 2020
https://doi.org/10.12688/f1000research.27019.2
Software Tool Article metrics
Revised
Automated cell tracking using StarDist and TrackMate
[version 2; peer review: 3 approved]
Peer Reviewers Lachlan W. Whitehead; Ignacio Arganda-Carreras; Vinay Swaminathan
  • Funders
  • Academy of Finland
  • National Cancer Center Finland
  • American Institute for Cancer Research
  • Sigrid Juselius Foundation
  • Medical Research Council
  • Åbo Akademi University Research Foundation
  • National Institutes of Health
  • Cancer Research Institute
LATEST VERSION PUBLISHED 21 Dec 2020
https://doi.org/10.12688/f1000research.26215.1
Research Article metrics
Antibacterial activity in secondary metabolite extracts of heterotrophic bacteria against Vibrio alginolyticus, Aeromonas hydrophila, and Pseudomonas aeruginosa
[version 1; peer review: 2 approved]
Peer Reviewers Agung Damar Syakti; Yuhanis Mhd Bakri
PUBLISHED 21 Dec 2020
https://doi.org/10.12688/f1000research.27892.1
Method Article metrics
A Method to adjust for measurement error in multiple exposure variables measured with correlated errors in the absence of an internal validation study
[version 1; peer review: 1 approved, 1 approved with reservations]
Peer Reviewers Erica Ponzi; Kesaobaka Molebatsi
  • Funders
  • Alliance for Accelerating Excellence in Science in Africa
  • African Academy of Sciences
  • New Partnership for Africa's Development
  • Department for International Development, UK Government
  • Wellcome Trust
PUBLISHED 18 Dec 2020
https://doi.org/10.12688/f1000research.26459.1
Software Tool Article metrics PEER REVIEW DISCONTINUED
Uncovering host-microbiome interactions in global systems with collaborative programming: a novel approach integrating social and data sciences
[version 1; peer review: 1 approved with reservations]
Peer Reviewers Sucheta Tripathy
  • Funder
  • University of South Florida
PUBLISHED 17 Dec 2020
https://doi.org/10.12688/f1000research.26246.1
Research Article metrics
The effect of an end-effector type of robot-assisted gait training on patients with Guillain-Barre syndrome: a cross-sectional study
[version 1; peer review: 1 approved, 1 approved with reservations]
Peer Reviewers Jong Moon Kim; Carlos A Cifuentes
PUBLISHED 16 Dec 2020
https://doi.org/10.12688/f1000research.26236.1
Review metrics
Cardiovascular protection effect of chlorogenic acid: focus on the molecular mechanism
[version 1; peer review: 1 approved, 2 approved with reservations]
Peer Reviewers Katalina Muñoz-Durango; Arrigo F. G Cicero; Suowen Xu
  • Funder
  • Universitas Brawijaya
PUBLISHED 15 Dec 2020
https://doi.org/10.12688/f1000research.20916.2
Method Article metrics
Revised
Fast effect size shrinkage software for beta-binomial models of allelic imbalance
[version 2; peer review: 1 approved, 2 approved with reservations]
Peer Reviewers Matthew Stephens; Jarad Niemi and Ignacio Alvarez-Castro; Ernest Turro
  • Funder
  • National Institutes of Health
LATEST VERSION PUBLISHED 14 Dec 2020
https://doi.org/10.12688/f1000research.27262.1
Method Article metrics
A pipeline to analyse time-course gene expression data
[version 1; peer review: 2 approved with reservations]
Peer Reviewers Michael I. Love; Rodolphe Thiébaut
  • Funders
  • U.S. Department of Energy
  • École Normale Supérieure
  • Gordon and Betty Moore Foundation
  • Alfred P. Sloan Foundation
PUBLISHED 11 Dec 2020
https://doi.org/10.12688/f1000research.22226.3
Study Protocol metrics
Revised
Methods used to meta-analyse results from interrupted time series studies: A methodological systematic review protocol
[version 3; peer review: 2 approved, 1 approved with reservations]
Peer Reviewers Christopher James Rose; Alexandra McAleenan; Tim Mathes
  • Funders
  • National Health and Medical Research Council
  • Department of Education, Employment and Workplace Relations, Australian Government
LATEST VERSION PUBLISHED 11 Dec 2020
2,081-2,100 of 5,762 ARTICLES
Articles
We publish a wide range of article types in science, engineering, medicine, social sciences and humanities, with no editorial biases.
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